Article
A powerful regression-based method for admixture mapping of isolation across the genome of hybrids.
Molecular ecology - 1 Mar 2009
Gompert Zachariah, Buerkle C Alex
Abstract excerpt
We propose a novel method that uses natural admixture between divergent lineages (hybridization) to investigate the genetic architecture of reproductive isolation and adaptive introgression. Our method employs multinomial regression to estimate genomic clines and to quantify introgression for individual loci relative to the genomic background (clines in genotype frequency along a genomic admixture gradient). Loci...
Topics
- Alleles
- Animals
- Computer Simulation
- Gene Frequency
- Genetic Drift
- Genetics, Population
- Genomics
- Helianthus
- Hybridization, Genetic
- Logistic Models
- Mice
- Models, Genetic
- Reproduction
- Selection, Genetic