Article
Linking functional molecular variation with environmental gradients: myosin gene diversity in a crustacean broadly distributed across variable thermal environments.
Gene - 15 May 2009
Rock J, Magnay J L, Beech S, El Haj A J, Goldspink G, Lunt D H, Whiteley N M
Abstract excerpt
To investigate the molecular basis of temperature adaptation in natural populations we used the candidate gene approach, targeting the myosin heavy chain (MyHC) gene. The functional effects of genetic variation in MyHC have been well characterised, and changes in the flexibility of the surface loops 1 and 2, caused by modulations in length, amino acid composition and charge can play an important role in thermal...
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