Novel mutations of CHST6 in Iranian patients with macular corneal dystrophy.

Abstract excerpt

PURPOSE: To characterize mutations within the carbohydrate sulfotransferase 6 (CHST6) gene in Iranian subjects from 12 families with macular corneal dystrophy (MCD). METHODS: Genomic DNA was extracted from peripheral blood of 20 affected patients and 60 healthy volunteers followed by polymerase chain reaction (PCR) and direct sequencing of the CHST6 coding region. The observed nucleotide sequences were then...

Topics

Join the communities discussing this publication.

• Amino Acid Sequence
• Binding Sites
• Case-Control Studies
• Corneal Dystrophies, Hereditary
• DNA Mutational Analysis