Article
Virulence factor genotypes of Helicobacter pylori affect cure rates of eradication therapy.
Archivum immunologiae et therapiae experimentalis - 1 Jan 2000
Sugimoto Mitsushige, Yamaoka Yoshio
Abstract excerpt
The cure rates of Helicobacter pylori infection by using a combination of a proton pump inhibitor (PPI) and antimicrobial agents are mainly influenced by bacterial susceptibility to antimicrobial agents and the magnitude of acid inhibition during the treatment. Currently used empirical triple therapies do not reliably produce a > or =80% cure rate on an intention-to-treat basis. Therefore, tailored regimens based...
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