Article
Optimizing the treatment of chronic hepatitis due to hepatitis C virus genotypes 2 and 3: a review.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jan 2009
Tarantino Giuseppe, Craxì Antonio
Abstract excerpt
Recently several randomized trials involving exclusively HCV 2 and 3 patients have explored the possibility of reducing the duration of therapy with PEG IFNs and ribavirin to 12-16 weeks. Among these, the largest studies (ACCELERATE, NORTH-C and NORDynamIC) have failed to demonstrate, by intention-to-treat analysis, that short treatment is non-inferior to the standard duration of 24 weeks originated by phase 3...
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