Article
HIV coinfection and antiretroviral therapy enhances liver steatosis in patients with hepatitis C, but only in those infected by HCV genotype other than 3.
Antiviral therapy - 1 Jan 2008
Borghi Vanni, Puoti Massimo, Mussini Cristina, Bellelli Stefania, Angeletti Claudio, Sabbatini Francesca, Prati Francesca, Cossarizza Andrea, Esposito Roberto
Abstract excerpt
BACKGROUND: Liver steatosis is a common finding in hepatitis C virus (HCV) infection and is associated with an increased progression of the disease. However, HCV genotype 3 steatosis presents a peculiar and virus-induced pathogenesis. We analysed the effect of HIV coinfection and antiretroviral therapy on hepatic steatosis and the effect of the steatosis on fibrosis in patients with or without HCV genotype 3...
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