Article
Genotypic determination by PCR-RFLP of human papillomavirus in normal oral mucosa, oral leukoplakia and oral squamous cell carcinoma samples in Madrid (Spain).
Anticancer research - 1 Jan 2000
Llamas-Martínez Silvia, Esparza-Gómez German, Campo-Trapero Julián, Cancela-Rodríguez Paloma, Bascones-Martínez Antonio, Moreno-López Luis Alberto, García-Núñez Juan Antonio, Cerero-Lapiedra Rocío
Abstract excerpt
BACKGROUND: Human papillomaviruses (HPVs), especially genotypes 16 and 18, are considered to be human carcinogens by the International Agency for Research on Cancer (IARC). They are the most important etiological agents of uterine cervix cancer but their true role in oral carcinogenesis is controversial. OBJECTIVES: To detect the presence of HPV genome genotypes in oral leukoplakia and oral squamous cell...
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