Host and pathogen determinants of verocytotoxin-producing Escherichia coli-associated hemolytic uremic syndrome.

doi:10.1038/ki.2008.608

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Article

Host and pathogen determinants of verocytotoxin-producing Escherichia coli-associated hemolytic uremic syndrome.

Kidney international. Supplement - 1 Feb 2009

Karmali Mohamed A

Abstract excerpt

Verocytotoxin (VT)-producing Escherichia coli (VTEC) infection is associated with a spectrum of clinical manifestations that includes diarrhea, hemorrhagic colitis, and the hemolytic uremic syndrome (HUS). The occurrence of HUS in a minority of individuals in outbreaks of VTEC infection is a function of several pathogen and host factors. Pathogen factors include the inoculum size and serotype of the infecting...

Topics

Age Factors
Anti-Bacterial Agents
Antibodies, Bacterial
Escherichia coli Infections
Escherichia coli O157
Gastric Acid
Genetic Predisposition to Disease
Genomic Islands
Hemolytic-Uremic Syndrome
Humans
Risk Factors
Shiga Toxins
Stress, Physiological
Virulence
Virulence Factors

Source

Open in PubMed

Identifiers

PMID: 19180132
DOI: 10.1038/ki.2008.608

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