Article
Primary drug resistance in antiretroviral-naïve injection drug users.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Sept 2009
Tossonian Harout K, Raffa Jesse D, Grebely Jason, Viljoen Mark, Mead Annabel, Khara Milan, McLean Mark, Krishnamurthy Ashok, DeVlaming Stanley, Conway Brian
Abstract excerpt
OBJECTIVES: We evaluated the prevalence of primary HIV drug resistance in a population of 128 injection drug users (48 female) prior to initiating antiretroviral therapy. METHODS: Genotypic and phenotypic profiles were obtained retrospectively for the period June 1996 to February 2007. Genotypic drug resistance was defined as the presence of a major mutation (IAS-USA table, 2007 revision), adding revertants at...
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