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Article

A tip-localized RhoGAP controls cell polarity by globally inhibiting Rho GTPase at the cell apex.

Current biology : CB - 23 Dec 2008

Hwang Jae-Ung, Vernoud Vanessa, Szumlanski Amy, Nielsen Erik, Yang Zhenbiao

Abstract excerpt

BACKGROUND: Highly elongated eukaryotic cells (e.g., neuronal axons, fungal hyphae, and pollen tubes) are generated through continuous apically restricted growth (tip growth), which universally requires tip-localized Rho GTPases. We used the oscillating pollen tube as a model system to determine the function and regulation of Rho GTPases in tip growth. Our previous work showed that the spatiotemporal dynamics of...

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Identifiers

PMID: 19108776
DOI: 10.1016/j.cub.2008.11.057
PMCID: PMC2615002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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