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Monodemethylated polymethoxyflavones from sweet orange (<i>Citrus sinensis</i>) peel Inhibit growth of human lung cancer cells by apoptosis

9 Dec 2008

Abstract excerpt

Polymethoxyflavones (PMFs) are almost exclusively found in the Citrus genus, particularly in the peels of sweet orange (Citrus sinensis L. Osbeck) and mandarin (C. reticulate Blanco). We studied the effects of two major PMFs, namely, nobiletin and 3,5,6,7,8,3',4'-heptamethoxyflavone (HMF), and two major monodemethylated PMFs, namely 5-hydroxy-3,7,8,3',4'-pentamethoxyflavone (5HPMF), and...

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Identifiers

PMID: 19065586
DOI: 10.1002/mnfr.200800057

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