Article
Diagonal earlobe crease are associated with shorter telomere in male Japanese patients with metabolic syndrome.
Circulation journal : official journal of the Japanese Circulation Society - 1 Feb 2009
Higuchi Yoshihiro, Maeda Toyoki, Guan Jing-Zhi, Oyama Junichi, Sugano Masahiro, Makino Naoki
Abstract excerpt
BACKGROUND: Diagonal earlobe crease (ELC) have been proposed as a marker of generalized atherosclerosis, so in the present study it was investigated whether individuals with ELC have a shortened telomere, which correlates with an accelerated cell turnover and premature aging, leading to atherosclerosis. METHODS AND RESULTS: The mean terminal restriction fragment (TRF) was determined by Southern blot hybridization...
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