Article
Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome.
Genomics - 1 Mar 2009
Yoshida Tetsuro, Kato Kimihiko, Fujimaki Tetsuo, Yokoi Kiyoshi, Oguri Mitsutoshi, Watanabe Sachiro, Metoki Norifumi, Yoshida Hidemi, Satoh Kei, Aoyagi Yukitoshi, Nishigaki Yutaka, Tanaka Masashi, Nozawa Yoshinori, Yamada Yoshiji
Abstract excerpt
The purpose of the present study was to identify genetic variants that confer susceptibility to chronic kidney disease (CKD) in Japanese individuals with metabolic syndrome. The study population comprised 2150 Japanese individuals with metabolic syndrome, including 411 subjects with CKD [estimated glomerular filtration rate (eGFR) <50 mL/min/1.73m(2)] and 1739 controls (eGFR >/=60 mL/min/1.73m(2)). The genotypes...
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