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Article

Host glycosaminoglycan confers susceptibility to bacterial infection in Drosophila melanogaster.

Infection and immunity - 1 Feb 2009

Baron Miriam J, Wong Sandra L, Nybakken Kent, Carey Vincent J, Madoff Lawrence C

Abstract excerpt

Many pathogens engage host cell surface glycosaminoglycans, but redundancy in pathogen adhesins and host glycosaminoglycan-anchoring proteins (heparan sulfate proteoglycans) has limited the understanding of the importance of glycosaminoglycan binding during infection. The alpha C protein of group B streptococcus, a virulence determinant for this neonatal human pathogen, binds to host glycosaminoglycan and...

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Identifiers

PMID: 19047407
DOI: 10.1128/IAI.00995-08
PMCID: PMC2632041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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