Article
[Sudden blindness: consider Leber's hereditary optic neuropathy].
Nederlands tijdschrift voor geneeskunde - 25 Oct 2008
Schieving J H, de Vries B B A, Hol F, Stroink H
Abstract excerpt
In 3 young male patients, aged 10, 19 and 21 years respectively, sequential, severe, painless bilateral visual loss occurred. Ophthalmological examination revealed no other abnormalities and this delayed the diagnosis Leber's hereditary optic neuropathy (LHON). LHON is a mitochondrial genetic disease characterised by bilateral acute or subacute painless loss of central vision. LHON causes blindness, predominantly...
Topics
- Blindness
- Child
- DNA, Mitochondrial
- Diagnosis, Differential
- Humans
- Male
- Mutation
- Optic Atrophy, Hereditary, Leber
- Young Adult