Monogenic pigmentary skin disorders: genetics and pathophysiology.

Abstract excerpt

For centuries skin pigmentation has played a major societal role, and genetic disorders of skin pigmentation have always evoked the curiosity of both laypersons and physicians. Normal skin pigmentation is a complex process that begins with the synthesis of melanin within the melanocytes, followed by its transfer to neighboring keratinocytes where it is translocated to the upper pole of the nucleus and degraded as...

Topics

• Cell Proliferation
• Genetic Predisposition to Disease
• Humans
• Melanins
• Melanocytes
• Pigmentation Disorders