Article
Differential mRNA expression of the avian-specific toll-like receptor 15 between heterophils from Salmonella-susceptible and -resistant chickens.
Immunogenetics - 1 Jan 2009
Nerren Jessica R, Swaggerty Christina L, MacKinnon Kathryn M, Genovese Kenneth J, He Haiqi, Pevzner Igal, Kogut Michael H
Abstract excerpt
Pattern recognition receptors (PRRs) are essential for recognition of conserved molecular constituents found on infectious microbes. Toll-like receptors (TLRs) are a critical component of the PRR repertoire and are coupled to downstream production of cytokines, chemokines, and antimicrobial peptides by TLR adaptor proteins. Our laboratory previously demonstrated a role for TLR function in the differential innate...
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