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Article

A basic limitation on inferring phylogenies by pairwise sequence comparisons.

Journal of theoretical biology - 7 Feb 2009

Steel Mike

Abstract excerpt

Distance-based approaches in phylogenetics such as Neighbor-Joining are a fast and popular approach for building trees. These methods take pairs of sequences, and from them construct a value that, in expectation, is additive under a stochastic model of site substitution. Most models assume a dist...

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PMID: 19000697
DOI: 10.1016/j.jtbi.2008.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19000697-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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