Article
Identification of three mutant loci conferring carboxin-resistance and development of a novel transformation system in Aspergillus oryzae.
Fungal genetics and biology : FG & B - 1 Jan 2009
Shima Yoko, Ito Yasuhiro, Kaneko Satoshi, Hatabayashi Hidemi, Watanabe Yasushi, Adachi Yoshikazu, Yabe Kimiko
Abstract excerpt
Mutants exhibiting resistance to the fungicide, carboxin, were isolated from Aspergillus oryzae, and the mutations in the three gene loci, which encode succinate dehydrogenase (SDH) B, C, and D subunits, were identified to be independently responsible for the resistance. A structural model of the SDH revealed the different mechanisms that confer carboxin-resistance in different mutations. The mutant AosdhB gene...
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