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Article

Searching for genes underlying behavior: lessons from circadian rhythms.

Science (New York, N.Y.) - 7 Nov 2008

Takahashi Joseph S, Shimomura Kazuhiro, Kumar Vivek

Abstract excerpt

The success of forward genetic (from phenotype to gene) approaches to uncover genes that drive the molecular mechanism of circadian clocks and control circadian behavior has been unprecedented. Links among genes, cells, neural circuits, and circadian behavior have been uncovered in the Drosophila and mammalian systems, demonstrating the feasibility of finding single genes that have major effects on behavior. Why...

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Identifiers

PMID: 18988844
DOI: 10.1126/science.1158822
PMCID: PMC3744585

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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