Article
The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review.
Journal of inherited metabolic disease - 1 Dec 2008
Wamelink M M C, Struys E A, Jakobs C
Abstract excerpt
The recent discovery of two defects (ribose-5-phosphate isomerase deficiency and transaldolase deficiency) in the reversible part of the pentose phosphate pathway (PPP) has stimulated interest in this pathway. In this review we describe the functions of the PPP, its relation to other pathways of carbohydrate metabolism and an overview of the metabolic defects in the reversible part of the PPP.
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