Article
[Causes and clinical implications of sperm DNA damages].
Gynecologie, obstetrique & fertilite - 1 Nov 2008
Hazout A, Menezo Y, Madelenat P, Yazbeck C, Selva J, Cohen-Bacrie P
Abstract excerpt
Numerous recent studies involve DNA damages associated with poor fertilization rates, early embryo development defect, and poor quality of conceptus following Assisted Reproductive Technologies (ART). The authors denounce a particularly high rate of miscarriages and childhood cancer or dominant genetic mutations such as achondroplasia, Apert syndrome or aberrant gene imprinting such as Angelman and Beckwith...
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