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Natural transfer of sulphonamide and ampicillin resistance between Escherichia coli residing in the human intestine

18 Oct 2008

Abstract excerpt

OBJECTIVES: The aim of this study was to investigate whether the sulphonamide resistance gene sul2 could be transferred between Escherichia coli in the human gut. METHODS: Nine volunteers ingested a 10(9) cfu suspension of sulphonamide-susceptible, rifampicin-resistant E. coli recipients of human origin. Three hours later, they ingested a 10(7) cfu suspension of a sulphonamide-resistant (MIC>1024 mg/L) E. coli...

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PMID: 18957394
DOI: 10.1093/jac/dkn437

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