Predominance of Mother-to-Child Transmission of Helicobacter pylori Infection Detected by Random Amplified Polymorphic DNA Fingerprinting Analysis in Japanese Families

Abstract excerpt

BACKGROUND: Helicobacter pylori (H. pylori) is one of the most common bacterial pathogens in humans but the route of transmission remains unclear. We investigated transmission by DNA fingerprinting analysis of cultured H. pylori from pediatric patients and their family members. METHODS: Forty-two index patients with a mean age of 11.7 years (range, 4-19) were diagnosed as having H. pylori gastritis with or...

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