Article
Relationship between vitamin D receptor BsmI and FokI polymorphisms and anthropometric and biochemical parameters describing metabolic syndrome.
The aging male : the official journal of the International Society for the Study of the Aging Male - 1 Sept 2008
Filus Alicja, Trzmiel Anna, Kuliczkowska-Płaksej Justyna, Tworowska Urszula, Jedrzejuk Diana, Milewicz Andrzej, Medraś Marek
Abstract excerpt
INTRODUCTION: It was found that vitamin D may have a direct effect on adipocyte differentiation and metabolism and might be involved in the glucose regulation of insulin secretion, as suggested from the discovery of a nuclear localization of 1,25-(OH)(2)D(3) in pancreatic islets. In recent years, several polymorphisms in the VDR gene which are able to alter the activity of VDR protein have been described. The...
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