Article
Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses.
PLoS pathogens - 26 Sept 2008
Vijaykrishna Dhanasekaran, Bahl Justin, Riley Steven, Duan Lian, Zhang Jin Xia, Chen Honglin, Peiris J S Malik, Smith Gavin J D, Guan Yi
Abstract excerpt
The highly pathogenic avian influenza (HPAI) H5N1 virus lineage has undergone extensive genetic reassortment with viruses from different sources to produce numerous H5N1 genotypes, and also developed into multiple genetically distinct sublineages in China. From there, the virus has spread to over 60 countries. The ecological success of this virus in diverse species of both poultry and wild birds with frequent...
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