Article
Convenient syntheses of homopropargylglycine.
Journal of peptide science : an official publication of the European Peptide Society - 1 Oct 2008
Dong Shouliang, Merkel Lars, Moroder Luis, Budisa Nediljko
Abstract excerpt
An improved classic Strecker synthesis was elaborated leading to racemic homopropargylglycine (Hpg) in 61% overall yield, while an asymmetric Strecker reaction produced Hpg and the higher homolog 2-aminohept-6-ynoic acid in significantly higher yields and over 80% ee.
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