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Article

How can we realize the promise of personalized antidepressant medicines?

Nature reviews. Neuroscience - 1 Aug 2008

Holsboer Florian

Abstract excerpt

Personalized medication that is based on pharmacogenetic data has long been expected to improve the efficacy of treatments for neurological and psychiatric disorders, including depression. However, the complexity of the regulation of gene transcription and its interactions with environmental factors means that straightforward translation of individual genetic information into tailored treatment is unlikely....

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PMID: 18628772
DOI: 10.1038/nrn2453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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