Article
The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 2008
Lorenzen Marcé D, Gnirke Andreas, Margolis Jonathan, Garnes Jeffrey, Campbell Margie, Stuart Jeffrey J, Aggarwal Rajat, Richards Stephen, Park Yoonseong, Beeman Richard W
Abstract excerpt
Maternal-Effect Dominant Embryonic Arrest ("Medea") factors are selfish nuclear elements that combine maternal-lethal and zygotic-rescue activities to gain a postzygotic survival advantage. We show that Medea(1) activity in Tribolium castaneum is associated with a composite Tc1 transposon inserted just downstream of the neurotransmitter reuptake symporter bloated tubules (blot), whose Drosophila ortholog has both...
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