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Epstein-Barr Virus BART MicroRNAs Are Produced from a Large Intron prior to Splicing

10 Jul 2008

Abstract excerpt

Latent Epstein-Barr virus (EBV) infection is associated with several lymphoproliferative disorders, including posttransplant lymphoma, Hodgkin's disease, and Burkitt's lymphoma, as well as nasopharyngeal carcinoma (NPC). Twenty-nine microRNAs (miRNAs) have been identified that are transcribed during latent infection from three clusters in the EBV genome. Two of the three clusters of miRNAs are made from the BamHI...

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PMID: 18614630
DOI: 10.1128/jvi.00785-08

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