Article
Apolipoprotein E polymorphism in normal Han Chinese population: frequency and effect on lipid parameters.
Molecular biology reports - 1 Jul 2009
Liang Shu, Pan Min, Geng Hai-Hua, Chen Hui, Gu Li-Qun, Qin Xiao-Tong, Qian Jin-Jun, Zhu Jian-Hua, Liu Chun-Feng
Abstract excerpt
Apolipoprotein E (ApoE) genotypes were studied in order to determine the prevalence and effect on lipid parameters in normal Han Chinese population. Fragments of ApoE gene forth exon containing codon 112 and 158 polymorphic locus were amplified by PCR, and then digested with Cfo I endonuclease. Genotypes and alleles frequencies of 168 healthy Han Chinese were calculated. The frequency of genotypes epsilon3/3,...
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