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Article

Smoking increases the risk of high-grade vaginal intraepithelial neoplasia in women with oncogenic human papillomavirus.

Gynecologic oncology - 1 Sept 2008

Sherman Jessica F, Mount Sharon L, Evans Mark F, Skelly Joan, Simmons-Arnold Linda, Eltabbakh Gamal H

Abstract excerpt

OBJECTIVES: In a large retrospective study, the association of smoking with human papillomavirus (HPV) genotype and vaginal intraepithelial neoplasia (VAIN) grade was analyzed. METHODS: A SNOMED search was performed for vaginal biopsy or resection specimens diagnosed as VAIN over an 11-year period. The diagnosis of VAIN grade was confirmed by histological review. HPV genotype was determined by GP5+/6+ PCR and dot...

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Identifiers

PMID: 18586314
DOI: 10.1016/j.ygyno.2008.05.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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