Article
A molecular clutch disables flagella in the Bacillus subtilis biofilm.
Science (New York, N.Y.) - 20 Jun 2008
Blair Kris M, Turner Linda, Winkelman Jared T, Berg Howard C, Kearns Daniel B
Abstract excerpt
Biofilms are multicellular aggregates of sessile bacteria encased by an extracellular matrix and are important medically as a source of drug-resistant microbes. In Bacillus subtilis, we found that an operon required for biofilm matrix biosynthesis also encoded an inhibitor of motility, EpsE. EpsE arrested flagellar rotation in a manner similar to that of a clutch, by disengaging motor force-generating elements in...
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