Article
Psychiatric genetics: progress amid controversy.
Nature reviews. Genetics - 1 Jul 2008
Burmeister Margit, McInnis Melvin G, Zöllner Sebastian
Abstract excerpt
Several psychiatric disorders--such as bipolar disorder, schizophrenia and autism--are highly heritable, yet identifying their genetic basis has been challenging, with most discoveries failing to be replicated. However, inroads have been made by the incorporation of intermediate traits (endophenotypes) and of environmental factors into genetic analyses, and through the identification of rare inherited variants...
Topics
- Animals
- Genetic Predisposition to Disease
- Genetic Variation
- Genome, Human
- Humans
- Mental Disorders
- Risk Factors