Article
Effects of 0.60 PPM nitrogen dioxide on circulating and bronchoalveolar lavage lymphocyte phenotypes in healthy subjects.
Environmental research - 1 Jun 1991
Rubinstein I, Reiss T F, Bigby B G, Stites D P, Boushey H A
Abstract excerpt
Nitrogen dioxide (NO2) is a common oxidant air pollutant. Animal studies have suggested that NO2 exposure causes a decrease in the numbers of some splenic lymphocyte subtypes and impairs lymphocyte-dependent immune responses. To investigate whether ambient levels of NO2 alter circulating and bronchoalveolar lavage fluid (BALF) human lymphocytes, we studied five healthy nonsmoking adult volunteers. In each...
Topics
- Adult
- Airway Resistance
- Antigens, CD
- Antigens, Differentiation
- Bronchoalveolar Lavage Fluid
- Bronchoscopy
- Female
- Forced Expiratory Volume
- Humans
- Lymphocytes
- Male