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MALDI-TOF mass spectrometry as a tool for differentiation of invasive and noninvasive<i>Streptococcus pyogenes</i>isolates

5 Jun 2008

Abstract excerpt

A novel mass spectral fingerprinting and proteomics approach using MALDI-TOF MS was applied to detect and identify protein biomarkers of group A Streptococcus (GAS) strains. Streptococcus pyogenes ATCC 700294 genome strain was compared with eight GAS clinical isolates to explore the ability of MALDI-TOF MS to differentiate isolates. Reference strains of other bacterial species were also analyzed and compared with...

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PMID: 18537829
DOI: 10.1111/j.1574-695x.2008.00428.x

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