Article
From human genetics and genomics to pharmacogenetics and pharmacogenomics: past lessons, future directions.
Drug metabolism reviews - 1 Jan 2008
Nebert Daniel W, Zhang Ge, Vesell Elliot S
Abstract excerpt
A brief history of human genetics and genomics is provided, comparing recent progress in those fields with that in pharmacogenetics and pharmacogenomics, which are subsets of genetics and genomics, respectively. Sequencing of the entire human genome, the mapping of common haplotypes of single-nucleotide polymorphisms (SNPs), and cost-effective genotyping technologies leading to genome-wide association (GWA)...
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