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Article

Association between the frequency of class II HLA antigens and the susceptibility to intrauterine infection of hepatitis B virus.

International journal of biological sciences - 25 Apr 2008

Xu Yuan-yong, Yu Ji-yun, Zhong Yan-wei, Song Hong-bin, Liu Hui-hui, Jia Lei-li, Li Shen-long, Xu Jian-qiu, Li Qiao

Abstract excerpt

Multiple factors determine the susceptibility to intrauterine hepatitis B virus (HBV) infection. These factors include the HBV structure, HBV mutation, HBV DNA level, placental barrier, the immune status of the mother, and the genetic make-ups of the newborn infants. Since HLA system is an integral component of the immune response, we hypothesized that the highly polymorphic HLA genes are the key determinants of...

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Share to Hepatitis B
Share to Hepatitis B Surface Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B Vaccines

Share to Histocompatibility Antigens Class II

Share to HLA-DRB1 Chains

Share to Immunoglobulins

Share to Infectious Disease Transmission, Vertical

Share to Pregnancy Complications, Infectious

Source

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Identifiers

PMID: 18463715
DOI: 10.7150/ijbs.4.111
PMCID: PMC2359901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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