Article
Identification of the yellow skin gene reveals a hybrid origin of the domestic chicken.
PLoS genetics - 29 Feb 2008
Eriksson Jonas, Larson Greger, Gunnarsson Ulrika, Bed'hom Bertrand, Tixier-Boichard Michele, Strömstedt Lina, Wright Dominic, Jungerius Annemieke, Vereijken Addie, Randi Ettore, Jensen Per, Andersson Leif
Abstract excerpt
Yellow skin is an abundant phenotype among domestic chickens and is caused by a recessive allele (W*Y) that allows deposition of yellow carotenoids in the skin. Here we show that yellow skin is caused by one or more cis-acting and tissue-specific regulatory mutation(s) that inhibit expression of BCDO2 (beta-carotene dioxygenase 2) in skin. Our data imply that carotenoids are taken up from the circulation in both...
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