Article
The prevalence of activated protein C (APC) resistance and factor V Leiden is significantly higher in patients with retinal vein occlusion without general risk factors. Case-control study and meta-analysis.
Thrombosis and haemostasis - 1 May 2008
Rehak Matus, Rehak Jiri, Müller Marc, Faude Susanne, Faude Frank, Siegemund Annelie, Krcova Vera, Slavik Ludek, Hasenclever Dirk, Scholz Markus, Wiedemann Peter
Abstract excerpt
Several small case-control studies have investigated whether factor V Leiden (FVL) is a risk factor for retinal vein occlusion (RVO) and generated conflicting data. To clarify this question we performed a large two-centre case-control study and a meta-analysis of published studies. Two hundred seven consecutive patients with RVO and a control group of 150 subjects were screened between 1996 and 2006. A systematic...
Topics
- Activated Protein C Resistance
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Case-Control Studies
- Czech Republic
- Factor V
- Female
- Genetic Predisposition to Disease
- Genetic Testing
- Germany