Article
Pathogenesis of renal disease due to enterohemorrhagic Escherichia coli in germ-free mice.
Infection and immunity - 1 Jul 2008
Eaton Kathryn A, Friedman David I, Francis Gayle J, Tyler Jessica S, Young Vincent B, Haeger Jennifer, Abu-Ali Galeb, Whittam Thomas S
Abstract excerpt
Enterohemorrhagic Escherichia coli (EHEC) is a food-borne pathogen that causes hemorrhagic colitis and acute renal failure. We used a germ-free mouse model to investigate the role of host factors, Shiga toxin 2 (Stx2), and bacterial strain in disease due to EHEC. Germ-free male and female Swiss-W...
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