Article
Kleine-Levin syndrome: a systematic study of 108 patients.
Annals of neurology - 1 Apr 2008
Arnulf Isabelle, Lin Ling, Gadoth Nathan, File Jennifer, Lecendreux Michel, Franco Patricia, Zeitzer Jamie, Lo Betty, Faraco Juliette H, Mignot Emmanuel
Abstract excerpt
OBJECTIVE: Kleine-Levin syndrome is a rare disorder characterized by relapsing-remitting episodes of hypersomnia, cognitive disturbances, and behavioral disturbances, such as hyperphagia and hypersexuality. METHODS: We collected detailed clinical data and blood samples on 108 patients, 79 parent pairs, and 108 matched control subjects. We measured biological markers and typed human leukocyte antigen genes DR and...
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