Article
Successful treatment of chronic myeloproliferative disease-unclassifiable (CMPD-U) with no chromosomal abnormalities by imatinib mesylate.
Internal medicine (Tokyo, Japan) - 1 Jan 2008
Iyama Satoshi, Matsunaga Takuya, Sato Tsutomu, Murase Kazuyuki, Araki Naoko, Takimoto Rishu, Kobune Masayoshi, Sagawa Tamotsu, Takayama Tetsuji, Niitsu Yoshiro
Abstract excerpt
We report a chronic myeloproliferative disease-unclassifiable (CMPD-U) patient who achieved hematological remission following imatinib mesylate (imatinib). Chromosomal and molecular analyses demonstrated no genetic abnormalities of c-abl, bcr-abl, c-kit or platelet-derived growth factor receptor (PDGFR) genes from hematopoietic cells. Although there has been one report of CMPD-U patient with chromosomal...
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