Sleep phenotypes of intellectual disability: a polysomnographic evaluation in subjects with Down syndrome and Fragile-X syndrome.

doi:10.1016/j.clinph.2008.03.004

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Sleep phenotypes of intellectual disability: a polysomnographic evaluation in subjects with Down syndrome and Fragile-X syndrome.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology - 1 Jun 2008

Miano Silvia, Bruni Oliviero, Elia Maurizio, Scifo Lidia, Smerieri Arianna, Trovato Alessia, Verrillo Elisabetta, Terzano Mario G, Ferri Raffaele

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OBJECTIVE: To analyze sleep architecture and NREM sleep alterations by means of the Cyclic Alternating Pattern (CAP) in children with Down syndrome (DS) and Fragile-X syndrome (fraX), the two most common causes of inherited mental retardation, in order to find out eventual alterations of their sleep microstructure related to their mental retardation phenotypes. METHODS: Fourteen patients affected by fraX (mean...

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Sleep phenotypes of intellectual disability: a polysomnographic evaluation in subjects with Down syndrome and Fragile-X syndrome.

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