Article
Early complement activation follows eversion carotid endarterectomy and correlates with the time of clamping of the carotid artery.
Molecular immunology - 1 Jun 2008
Széplaki Gábor, Hirschberg Kristóf, Gombos Tímea, Varga Lilian, Prohászka Zoltán, Dósa Edit, Acsády György, Karádi István, Garred Peter, Entz László, Füst George
Abstract excerpt
BACKGROUND: Complement activation plays an important role in ischemia/reperfusion (I/R) injury. The objective of the present study was to detect the presence and mechanism of complement activation in patients who underwent carotid endarterectomy (CEA). METHODS: Complement activation products C1rsC1-inhibitor, C4d, C3a and SC5b-9 and concentrations of C-reactive protein (CRP) were measured in samples serially...
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