Article
First cultivation and characterization of Mycobacterium ulcerans from the environment.
PLoS neglected tropical diseases - 26 Mar 2008
Portaels Françoise, Meyers Wayne M, Ablordey Anthony, Castro António G, Chemlal Karim, de Rijk Pim, Elsen Pierre, Fissette Krista, Fraga Alexandra G, Lee Richard, Mahrous Engy, Small Pamela L C, Stragier Pieter, Torrado Egídio, Van Aerde Anita, Silva Manuel T, Pedrosa Jorge
Abstract excerpt
BACKGROUND: Mycobacterium ulcerans disease, or Buruli ulcer (BU), is an indolent, necrotizing infection of skin, subcutaneous tissue and, occasionally, bones. It is the third most common human mycobacteriosis worldwide, after tuberculosis and leprosy. There is evidence that M. ulcerans is an environmental pathogen transmitted to humans from aquatic niches; however, well-characterized pure cultures of M. ulcerans...
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