Article
Necessity of nuclear and mitochondrial genome analysis prior to assisted reproductive techniques/intracytoplasmic sperm injection.
Indian journal of biochemistry & biophysics - 1 Dec 2007
Kumar Rakesh, Bhat Audesh, Bamezai R N K, Shamsi M B, Kumar R, Gupta N P, Ammini A C, Aron M, Sharma R K, Dada Rima
Abstract excerpt
Assisted reproductive technique (ART) has revolutionized the management of severe male factor infertility and in some countries 5% babies are conceived through ART/intra cytoplasmic sperm injection (ICSI). However, the carry-home live birth rate after several ART cycles is low (18-25%) and this is financially, physically and emotionally crippling for the couples. Genetic factors could lead to pre or...
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