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Comparison of the results of PCR-RFLP and reverse hybridization methods used in molecular diagnosis of FMF.

Genetic testing - 1 Mar 2008

Sahin Feride Iffet, Yilmaz Zerrin, Yurtcu Erkan, Baskin Esra

Abstract excerpt

Familial Mediterranean fever (FMF) is characterized by recurrent fever, serositis, and arthritis. Due to the abundance of mutations and clinical heterogeneity of the disease, different screening methods have been developed. In this study, we aimed to compare our findings of mutations determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) with reverse hybridization (RH)...

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PMID: 18307385
DOI: 10.1089/gte.2007.0085

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