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Article

Lactate modulates gene expression in human mesenchymal stem cells.

Langenbeck's archives of surgery - 1 May 2008

Zieker Derek, Schäfer Richard, Glatzle Jörg, Nieselt Kay, Coerper Stephan, Kluba Torsten, Northoff Hinnak, Königsrainer Alfred, Hunt Thomas K, Beckert Stefan

Abstract excerpt

PURPOSE: Surgical wounds are characterised by elevated tissue lactate concentrations. This accumulated lactate is capable of stimulating collagen synthesis and new vessel growth as well. Recently, it has been shown in vivo that lactate is also able to favour homing of stem cells. The aim of this...

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Source

Identifiers

PMID: 18273635
DOI: 10.1007/s00423-008-0286-6

Genes

MSC
BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18273635-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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