Article
Targeted gene deletion and phenotypic analysis of the Drosophila melanogaster seminal fluid protease inhibitor Acp62F.
Genetics - 1 Mar 2008
Mueller Jacob L, Linklater Jon R, Ravi Ram Kristipati, Chapman Tracey, Wolfner Mariana F
Abstract excerpt
Internally fertilizing organisms transfer a complex assortment of seminal fluid proteins, a substantial fraction of which are proteolysis regulators. In mammals, some seminal protease inhibitors have been implicated in male infertility and these same molecular classes of protease inhibitors are also found in Drosophila seminal fluid. Here, we tested the reproductive functions of the Drosophila melanogaster...
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